韩 达 课 题 组

韩 达 课 题 组

  • 71Liqi Wan#, Axin He#, Jinxing Li, Pei Guo*, Da Han*. High-Resolution NMR Structures of Intrastrand Hairpins Formed by CTG Trinucleotide Repeats. ACS Chem. Neurosci. 2024, 15, 4, 868–876. Read this online.

     

     

     

    72Mingzhi Zhang, Colin Yancey, Chao Zhang, Junyan Wang, Qian Ma, Linlin Yang, Rebecca Schulman*, Da Han*, Werihong Tan*, A DNA circuit that records molecular events. Science. Advances. 2024, 10, eadn3329.  Read this online.

     

     

     

     

    74. Linlin Yang#, Qian Tang#, Mingzhi Zhang, Yuan Tian, Xiaoxing Chen, Rui Xu, Qian Ma, Pei Guo*, Chao Zhang*, Da Han*. A spatially localized DNA linear classifier for cancer diagnosis. Nat Commun. 2024, 15, 4583. Read this online.

    73Chunying Li, Dan Wang, Haiyan Gao, Ting Fu, Lei He*, Da Han*, Weihong Tan*. Leveraging DNA-encoded Cell-mimics for Environment-adaptive Transmembrane Channel Release-induced Cell Death. Angew. Chem. Int. Ed. 2024, e202406186.  Read this online.

     

     

     

    76. Axin He, Liqi Wan, Yuchao Zhang, Zhengzheng Yan, Pei Guo*, Da Han*, Weihong Tan*. Structure-based investigation of a DNA aptamer targeting PTK7 reveals an intricate 3D fold guiding functional optimization. Proc Natl Acad Sci U S A2024, 121(29), e2404060121. Read this online

     

    78. Nannan Diao, Jianing Hou, Xinyu Peng, Yaru Wang, Axin He, Haiyan Gao, Linlin Yang, Pei Guo, Junyan Wang*, Da Han*. Multiplexed and Quantitative Imaging of Live-Cell Membrane Proteins by a Precise and Controllable DNA-Encoded Amplification Reaction. Angew Chem Int Ed Engl. 2024, e202406330. Read this online

     

     

     

     

    79.  Minghui Song, Junyan Wang, Jianing Hou, Ting Fu, Yawei Feng, Wenyi Lv, Feng Ge, Ruizi Peng* Da Han*, and Weihong Tan*. Multiplexed In Situ Imaging of Site-Specific m6A Methylation with Proximity Hybridization Followed by Primer Exchange Amplification (m6A-PHPEA). ACS Nano. 2024, 18, 40, 27537–27546.  Read this online

     

     

     

     

    75. Axin He, Fangfang Xia,  Da Ha*, Qinglai Yang*, and Weihong Tan*. Self-assembled amphiphilic NIR-II emissive nano-micelles for imaging-guided photothermal therapy of colorectal cancer Science China Chemistry. 2024, 67 (8), 2767-2774.  Read this online

     

    77. Jiao Yang, Da Han. "Building DNA Computing System for Smart Biosensing and Clinical Diagnosis" in DNA Nanotechnology for Cell Research, Wiley (2024). Book Chapters. Read this online

     

     

     

     

    80.  Xinglei Su, Qiangting Zheng, Xuehao Xiu, Qiong Zhao, Yudong Wang, Da Han* and Ping Song*. 

    Challenges and prospects in utilizing technologies for gene fusion analysis in cancer diagnostics. Med-X. 2024, 2(1). Read this online 

    82. Zixi Lai#, Di Jin#, Yuan Tian#, Xiaoxing Chen, Da Han, Haige Chen*, Junyan Wang*, Yang Yang*.  Enhanced Sensitivity of Cell Identification in Complex Environments Using Chirally Inverted L-DNA-Based Logic Devices. Adv. Sci. 2024, 2410642. Read this online 

     

    81.  Xinyu Peng, Xiaoyan Teng, Qian Ma*, Da Han*. Serum Circulating mRNA Panel for the Early Detection of Gastric Cancer: A Potential Biomarker Test. ChemMedChem 2024, e202400523. Read this online 

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    62. Tingting Zheng#, Qian Tang#, Liqi Wan#, Yumeng Zhao, Rui Xu, Xuemei Xu, Haowen Li, Da Han*. Controlled Self-Assembly of the Catalytic Core of Hydrolases Using DNA Scaffolds. Nano Letters, 2023, 23 (6), 2081. Read this online.

    63. Liqing Qi#, Yuan Tian#, Na Li, Menghan Mao, Xiaohong Fang*, Da Han*. Engineering Circular Aptamer Assemblies with Tunable Selectivity to Cell Membrane Antigens In Vitro and In Vivo. ACS Appl Mater Interfaces, 2023, 15 (10), 12822.  Read this online.

     

    64. Junlan Liu, Chao Zhang, Jinxing Song, Qin Zhang, Rongjun Zhang, Mingzhi Zhang, Da Han*, Werihong Tan*.Unlocking Genetic Profiles with a Programmable DNA-Powered Decoding Circuit. Adv Sci2023, e2206343. Read this online.

     

     

     

    65. Xiaoyan Teng, Yu Wang, Liuxia You, Lirong Wei, Chao Zhang*, and Yuzhen Du*. Screening a DNA Aptamer Specifically Targeting Integrin beta3 and Partially Inhibiting Tumor Cell Migration. Anal Chem, 2023, 95 (33), 12406.  Read this online.

     

     

     

    66. Rui Xu, Qian Tang, Yiwen Ying and Da Han*, Surface Functionalization of Extracellular Vesicles with Nucleic Acids towards Biomedical Applications, Current Topics in Medicinal Chemistry, 2023; 23 (14) .   Read this online.

     

     

     

    67Mingzhi Zhang, Da Han*, Concept, Development and Applications of DNA Computation. Fundamental Research 2023. Read this online.

     

     

     

    68. Yuqing Li#, Xueliang Liu#, Lu Yu,  Xin Huang, Xuan Wang, Da Han*, Yu Yang*, Zhuang Liu*. Covalent LYTAC Enabled by DNA Aptamers for Immune Checkpoint Degradation Therapy. Journal of the American Chemical Society2023, 145 (45), 24506-24521. Read this online. 

    69Yuan Tian, Yanyan Miao, Pei Guo,  Junyan Wang*, Da Han*. Insulin-like Growth Factor 2-Tagged Aptamer Chimeras (ITACs) Modular Assembly for Targeted and Efficient Degradation of Two Membrane Proteins. Angew Chem Int Ed Engl2023, e202316089. Read this online.

     

     

     

  • 54. Chao Zhang, Tingting Zheng, Qian Ma, Linlin Yang, Mingzhi Zhang, Junyan Wang, Xiaoyan Teng, Yanyan Miao, Hsiao-chu Lin, Yang Yang*, Da Han*. Logical Analysis of Multiple Single-Nucleotide-Polymorphisms with Programmable DNA Molecular Computation for Clinical Diagnostics. Angew. Chem. Int. Ed., 2022, 61, e202117658.  Read this online.

    53. Sandeepa Vittala, Yumeng Zhao, Da Han*. Programmed Assembly of DNA templates by Silver Nanowires. ChemPlusChem, 2022, 87, e202100478. Read this online.

    55. Yiwen Ying, Qian Tang, Da Han*, Shan Mou*. Nucleic Acid Nanotechnology for Diagnostics and Therapeutics in Acute Kidney Injury. International Journal of Molecular Sciences, 2022, 23(6), 3093. Read this online.

     

    61. Qian Ma, Mingzhi Zhang, Chao Zhang*, Xiaoyan Teng, Linlin Yang, Yuan Tian, Junyan Wang, Da Han*, and Weihong Tan*.An automated DNA computing platform for rapid etiological diagnostics. Science Advances, 2022, 8(47), eade0453.  Read this online.

     

    59. Linyi Deng, Pei Guo, Da Han*, Weihong Tan. Sensing miRNAs for disease diagnostics,  Analysis & Sensing. 2022, e202200083.Read this online.

     

    56. Jie Yi, Liqi Wan, Yuan Liu, Sik Lok Lam, Ho Yin Edwin Chan*, Da Han*, Pei Guo*.NMR solution structures of d(GGCCTG)n repeats associated with spinocerebellar ataxia type 36, International Journal of Biological Macromolecules,Volume 201, 2022, 607-615. Read this online.

     

    57. Cai Yang, Haitao Zhao, Yang Sun, Cheng Wang, Xinyao Geng, Ruowen Wang*, Lumin Tang, Da Han, Jianjun Liu*, Weihong Tan*, Programmable manipulation of oligonucleotide–albumin interaction for elongated circulation time, Nucleic Acids Research, Volume 50, Issue 6, 8 April 2022, 3083–3095. Read this online.

     

    58. Pei Guo*, Da Han*, Targeting Pathogenic DNA and RNA Repeats: A Conceptual Therapeutic Way for Repeat Expansion Diseases. Chemistry – A European Journal. 2022, 28, e202201749.Read this online.

     

    60. Dandan Chao, Xuemei Xu, Yanyan Miao, Linlin Yang, Qianqian Gao, Rui Xu, Yuan Tian, Yumeng Zhao, Yuzhen Du*, Da Han*. Covalent stabilization of DNA nanostructures on cell membranes for efficient surface receptor-mediated labeling and function regulations. Science China Chemistry, 65, 2327–2334 (2022). Read this online.

  • 45. Yike Li, Jinqi Deng, Ziwei Han, Chao Liu, Fei Tian, Rui Xu, Da Han*, Shaohua Zhang*, Jiashu Sun*. Molecular Identification of Tumor-Derived Extracellular Vesicles Using Thermophoresis-Mediated DNA computation. Journal of the American Chemistry Society, 2021, 143(3): 1290-1295. Read this online.

    46. Chao Zhang#, Tingting Zheng#, Hua Wang, Wei Chen, Xiaoye Huang, Jianqi Liang, Liping Qiu, Da Han*, Weihong Tan*. Rapid One-Pot Detection of SARS-CoV-2 Based on a Lateral Flow Assay in Clinical Samples. Analytical Chemistry, 2021, 93(7): 3325-3330. Read this online.

    47. Da Han*, Xuemei Xu. DNA-Guided Programmable Protein Assemblies for Biomedical Applications. ChemPlusChem, 2021, 86: 284-290. Read this online.

    48. Chao Zhang#, Tingting Zheng#, Hongliagn Fan, Tao Zhang*, Da Han*. Aligner-Mediated Cleavage-Based Isothermal Amplification for SARS-CoV-2 RNA Detection.  ACS Applied Bio Materials, 2021, 4. 3805-3810. Read this online.

    49. Yanyan Miao#, Qianqian Gao#, Menghan Mao, Chao Zhang, Liqun Yang, Yang Yang, Da Han*. Bispecific Aptamer Chimeras Enable Targeted Protein Degradation on Cell Membranes. Angew. Chem. Int. Ed., 2021, 60(22): 11267-11271. Read this online.

    44. Yongxi Zhao#, Xiaolei Zuo#, Qian Li#, ..., Da Han, ... Chao Zhang, ...Chaoyong Yang*, Xiao-Bing Zhang*, Huanghao Yang*, Weihong Tan*, Chunhai Fan*. Nucleic Acid Analysis. SCIENCE CHINA Chemistry, 2021, 64: 171-203. Read this online.

    50. Qian Ma, Chao Zhang, Mingzhi Zhang, Da Han*, Weihong Tan*. DNA Computing: Principle, Construction, and Applications in Intelligent Diagnostics. Small Structures, 2021, 2, 2100051. Read this online.

    51. Yumeng Zhao#, Chao Zhang#, Linlin Yang, Xuemei Xu, Rui Xu, Qian Ma, Qian Tang, Yang Yang, Da Han*. Programmable and Site-Specific Patterning on DNA Origami Templates with Heterogeneous Condensation of Silver and Silica. Small, 2021, 17, 2103877. Read this online.

    52. Qian Tang, Da Han*. Obtaining Precise Molecular Information via DNA Nanotechnology. Membranes, 2021, 11, 683.  Read this online.

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    43. Cheng Lv#, Xiyao Gu#, Haowen Li, Yumeng Zhao, Donglei Yang, Weifeng Yu*, Da Han*, Juan Li, Weihong Tan*. Molecular Transport through a Biomimetic DNA Channel on Live Cell Membranes. ACS Nano, 2020, 14,11: 14616-14626. Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    42. Qianqian Gao#, Yumeng Zhao#, Kangli Xu, Chao Zhang, Qian Ma, Liqing Qi, Dandan Chao, Tingting Zheng, Linlin Yang, Yanyan Miao, Da Han*. Highly Specific, Single-step Cancer Cell Isolation with Multi-Aptamer-Mediated Proximity Ligation on Live Cell Membranes. Angew. Chem. Int. Ed. 2020, 59(52): 23564-23568. Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    41. Linlin Yang, Yumeng Zhao, Xuemei Xu, Kangli Xu, Mingzhi Zhang, Kui Huang, Huaizhi Kang*, Hsiao-chu Lin, Yang Yang*, Da Han*. An intelligent DNA nanorobot for autonomous anticoagulation. Angew. Chem. Int. Ed. 2020, 59(40): 17697-17704. Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    40. Chao Zhang, Yumeng Zhao, Xuemei Xu, Rui Xu, Haowen Li, Xiaoyan Teng, Yuzhen Du, Yanyan Miao, Hsiao-chu Lin, Da Han*. Cancer Diagnosis with DNA Molecular Computation. Nature Nanotechnology, 2020, 15: 709-715. Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    39. Sandeepa Kulala Vittala, Da Han*. DNA-Guided Assemblies toward Nanoelectronic Applications. ACS Applied Bio Materials, 2020, 3, 5: 2702-2722.  Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    38. Linlin Yang, Yanyan Miao, Da Han*. DNA Nanotechnology on Live Cell Membranes. Chemical Research in Chinese University, 2020, 36(2): 203-210. Read this online. 

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    37. Yifan Lyu, Ruizi Peneg, Hui Liu, Hailan Kuai, Liuting Mo, Da Han, Juan Li*, Weihong Tan*. Protocells Programmed through Artificial Reaction Networks. Chemical Science, 2020, 11: 631-642. Read this online. 

     
  • 36. Cheng Lv, Cai Yang, Ding Ding, Yang Sun, Ruowen Wang, Da Han*, Weihong Tan*. Endocytic Pathways and Intracellular Transport of Aptamer-drug Conjugates in Live Cells Monitored by Single-particle Tracking. Analytical Chemistry, 2019, 91(21): 13818-13823. Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    35. Da Han, Juan Li, Weihong Tan. CRIPSR Propels a Smart Hydrogel. Science, 2019, 365(6455): 754-755. Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    34. Xu Chang, Chao Zhang, Cheng Lv, Yang Sun, Mingzhi Zhang, Yumeng Zhao, Linlin Yang, Da Han*,Weihong Tan*. Construction of a Multiple-aptamer-based DNA Logic Device on Live Cell Membranes via Associative Toehold Activation for Accurate Cancer Cell Identification. Journal of the American Chemistry Society, 2019, 141(32): 12738-12743.  Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    33. Linlin Yang, Lingyan Meng, Jiaying Song, Yue Xiao, Ruowen Wang, Huaizhi Kang* and Da Han *. Dynamic Colloidal Nanoparticle Assembly Triggered by Aptamer-receptor Interactions on Live Cell Membranes. Chemical Science, 2019, 10, 7466-7471. Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    32. Ding Ding, Da Han, Juan Li and Weihong Tan. Improving Early Detection of Cancers by Profiling Extracellular Vesicles, Expert Review of Proteomics, 2019, 16, 545-547. Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    31. Yumeng Zhao and Da Han*. Nucleic Acid Based Intelligent Systems and Their Biomedical Applications. SCIENTIA SINICA Chimica (中国科学:化学), 2019, 62,1-7. 

     

  • 30. Yifan Lyu, Cuichen Wu, Charles Heinke, Da Han* (Co-corresponding author), Ren Cai, I-Ting Teng, Yuan Liu, Hui Liu, Xiao-Bing Zhang, Qiaoling Liu, Weihong Tan*. Constructing Smart Protocells with Built-in DNA Computational Core to Eliminate Exogenous Challenge. Journal of the American Chemical Society, 2018, 140 (22), 6912–6920. Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    29. Wanghua Wu, Tao Zhang, Da Han, Hongliang Fan, Guizhi Zhu, Xiong Ding, Cuichen Wu, Mingxu You, Liping Qiu, Juan Li, Liqin Zhang, Xiang Lian, Rong Hu, Ying Mu, Jianguang Zhou, Weihong Tan. Aligner-Mediated Cleavage of Nucleic Acids and Its Application to Isothermal Exponential Amplification. Chemical science, 2018, 9, 3050-3055. Read this online.

     

     

  • 28. Ruili Zhang, Shi Gao, Zhongliang Wang, Da Han, Lin Liu, Qingjie Ma, Weihong Tan, Jie Tian, Xiaoyuan Chen. Multifunctional Molecular Beacon Micelles for Intracellular mRNA Imaging and Synergistic Therapy in Multidrug Resistant Cancer Cells. Advanced functional materials, 2017, 27, 170127.  Read this online.

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    27. Mingxu You, Yifan Lv, Da Han (Co-first author), Liping Qiu, Qiaoling Liu, Tao Chen, Cuicheng Wu, Lu Peng, Liqin Zhang, Gang Bao and Weihong Tan. DNA Probes for monitoring dynamic and transient molecular encounters on live cell membranes. Nature Nanotechnology, 2017, 5, 453-459.  Read this online.

     

  • 26. Da Han and Weihong Tan. Molecular Engineering to Enhance Aptamer Functionality. In: Aptamers Selected by Cell SELEX for Theranostics, Springer, 2015. Book Chapters. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    25. Da Han, Cuichen Wu, Mingxu You, Tao Zhang, Shuo Wan, Tao Chen, Liping Qiu, Zheng Zheng, Hao Liang, and Weihong Tan. A Cascade Reaction Network Mimicking the Basic Functional Steps of Acquired Immune Response. Nature Chemistry, 2015, 7(10),835-841. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    24. Guizhi Zhu, Sena Cansiz, Mingxu You, Liping Qiu, Da Han, Liqin Zhang, Lei Mei, and Ting Fu and Weihong Tan. Nuclease-resistant Synthetic Drug-DNA Adducts: Programmable Drug-DNA Conjugation for Targeted Anticancer Drug Delivery. NPG Aisa Materials, 2015, 7, e169. (Full text)

     

     

  • 23. Da Han, Huaizhi Kang, Tao Zhang, Cuichen Wu, Cuisong Zhou, Mingxu You, Zhuo Chen, Xiaobing Zhang, Weihong Tan. Nucleic Acid Based Logical Systems (Concept paper), Chemistry-A European Journal, 2014,20, 5866-5873. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    22. Liping Qiu, Tao Chen, Ismail Öçsoy, Emir Yasun, Cuichen Wu, Guizhi Zhu, Mingxu You, Da Han, Jianhui Jiang, Ruqin Yu, Weihong Tan. A Cell-Targeted, Size-Photocontrollable, Nuclear-Uptake Nanodrug Delivery System for Drug-Resistant Cancer Therapy. Nano letter, 2014, 15, 457-463. (Full text)

     

     

     

     

     

     

  • 21. Cuichen Wu, Da Han (Co-first author), Tao Chen, Lu Peng, Guizhi Zhu, Mingxu You, Liping Qiu, Kwame Sefah, Xiao-Bing Zhang, Weihong Tan. Building a Multifunctional Aptamer-Based DNA Nanoassembly for Targeted Cancer Therapy. Journal of the American Chemical Society, 2013, 135, 18644-18650. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    20. Da Han, Guizhi Zhu, Cuichen Wu, Zhi Zhu, Tao Chen, Xiaobing Zhang and Weihong Tan. Engineering a Cell-Surface Aptamer Circuit for Targeted and Amplified Photodynamic Cancer Therapy. ACS Nano, 2013,7,2312-2319. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    19. Fujian Huang, Mingxu You, Da Han, Xiangling Xiong, Haojun Liang, and Weihong Tan. DNA Branch Migration Reactions Through Photocontrollable Toehold Formation. Journal of the American Chemical Society, 2013,135, 21, 7967-7973. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    18. Liping Qiu#, Cuichen Wu, Mingxu You, Da Han, Tao Chen, Guizhi Zhu, Jianhui Jiang, Ruqin YuQiu and Weihong Tan.A Targeted, Self-Delivered, and Photocontrolled Molecular Beacon for mRNA Detection in Living Cells. Journal of the American Chemical Society, 2013, 135, 12952-12955. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    17. Cuichen Wu, Tao Chen, Da Han, Mingxu You, Lu Peng, Sena Cansiz, Guizhi Zhu, Chunmei Li, Xiangling Xiong, Elizabeth Jimenez, Chaoyong James Yang, Weihong Tan. Engineering of Switchable Aptamer Micelle Flares for Molecular Imaging in Living Cells. ACS Nano,2013,7,5724-5731. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    16. Lu Peng, Cuichen Wu, Mingxu You, Da Han, Yan Chen, Ting Fu, Mao Ye, Weihong Tan. Engineering and Applications of DNA-Grafted Polymer Materials. Chemical Science, 2013, 5, 1928-1938. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    15. Tao Chen, Cuichen Wu, Elizabeth Jimenez, Zhi Zhu, Joshua Dajac, Mingxu You, Da Han, Xiaobing Zhang and Weihong Tan. DNA Micelle Flares for Intracellular mRNA Imaging and Gene Therapy. Angewandte Chemie,International Edition, 2013, 52, 2012-2016. (Full text)

     

     

     

  • 14. Da Han, Zhi Zhu, Cuichen Wu, Lu Peng, Leiji Zhou, Basri Gulbakan, Guizhi Zhu, Kathryn Williams, Weihong Tan. A Logical Molecular Circuit for Programmable and Autonomous Regulation of Protein Activity Using DNA Aptamer–Protein Interactions. Journal of the American Chemical Society, 2012, 134, 20797-20804. (C&EN-NEWS, http://cen.acs.org/articles/90/web/2012/12/DNA-Circuits-Control-Clotting-Protein.html ). (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    13. Mohammed I. Shukoor, Meghan O’Donoghue, Da Han, Tahir Bayrac, Ismail Ocsoy, Zhi Zhu and Weihong Tan. Aptamer-Nanoparticle Assembly for Logic-Based Detection. ACS Applied Materials & Interfaces, 2012, 4, 3007-3011. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    12. Lu Peng, Mingxu You, Quan Yuan, Cuichen Wu, Da Han, Yan Chen, Zhihua Zhong, Jiangeng Xue and Weihong Tan. Macroscopic Volume Change of Dynamic Hydrogels Induced by Reversible DNA Hybridization. Journal of the American Chemical Society, 2012, 134, 12302-12307. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    11. Cuichen Wu, Lu Peng, Mingxu You, Da Han, Tao Chen, Kathryn Williams, Chaoyong Yang and Weihong Tan. Engineering Molecular Beacons for Intracellular Imaging. International journal of molecular imaging, 2012,501579. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    10. Wei Zhang, Bo Zhang, Yulong Zhang, Da Han, Yongliang Zhou. Trapping Yeast Cells on PDMS Micropillar Array. Advanced Material Research, 2012, 476-478. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    9. Lu Peng, Zhi Zhu, Yan Chen, Da Han, and Weihong Tan. An exonuclease III and graphene oxide-aided assay for DNA detection. Biosensors and Bioelectronics, 2012, 35, 475-478. (Full text)

  • 8. Da Han, Chaoyong Yang and Weihong Tan. Functional materials for signal amplification of molecular beacons. In: Molecular Beacons, Springer, Heidelberg, 2011. Book Chapters. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    7. Da Han, Jin Huang, Zhi Zhu, Quan Yuan, Mingxu You, Yan Chen and Weihong Tan. Molecular Engineering of Photoresponsive Three-Dimensional DNA Nnanostructures. Chemical Communications, 2011, 47, 4670-4672. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    6. Pu Ying, Zhi Zhu, Da Han (Co-first author), Huixia Liu, Jun Liu, Jie Xia, Kejing Zhang and Weihong Tan. Insulin-Binding Aptamer-Conjugated Graphene Oxide for Insulin Detection. Analyst, 2011,136, 4138-4140. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    5. Kelong Wang, Mingxu You, Yan Chen, Da Han, Zhi Zhu, Jin Huang, Kathryn Williams, Chaoyong James Yang and Weihong Tan. Self-Assembly of a Bifunctional DNA Carrier for Drug Delivery. Angewandte Chemie, International Edition, 2011, 50, 6098-6101. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    4. Mingxu You, Yan Chen, Lu Peng, Da Han, Bincheng Yin, Bangce Ye and Weihong Tan. Engineering DNA Aptamers for Novel Analytical and Biomedical Applications. Chemical Science, 2011, 2, 1003-1010.   (Full text)

  • 3. Yunfei Zhang, Yan Chen, Da Han, Ismail Ösçoy and Weihong Tan. Aptamers Selected by Cell-SELEX for Application in Cancer Studies. Bioanalyst, 2010, 2, 907-918. (Full text)

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

     

    2. Mingxu You, Zhi Zhu, Haipeng Liu, Basri Gulbakan, Da Han, Ruowen Wang, Kathryn Williams and Weihong Tan. Pyrene-Assisted Efficient Photolysis of Disulfide Bonds in DNA-Based Molecular Engineering. ACS Applied Materials & Interfaces, 2010, 2, 3601-3605. (Full text)

     

     

     

  • 1. Yuan Li, Da Han, Shumin Han, Xilin Zhu, Lin Hu, Zhong Zhang, Yuwen Liu. Effect of Rare Earth Elements on Electrochemical Properties of La-Mg-Ni-Based Hydrogen Storage Alloys. International Journal of Hydrogen Energy, 2009, 34, 1399-1404. (Full text)

     

     

     

     

70Yang Wang#, Junyan Wang#, Zhenzhen Yan, Jianing Hou, Liqi Wan, Yinquan Yang, Yu Liu, Jie Yi, Pei Guo*, Da Han*.Structural investigation of pathogenic RFC1 AAGGG pentanucleotide repeats reveals a role of G-quadruplex in dysregulated gene expression in CANVAS. Nucleic Acids Research 2024, gkae032.  Read this online.